Wednesday, February 21, 2024
Wednesday, February 21, 2024
HomeLifestyleAlzheimer's risk decreases in men who take Viagra and similar prescriptions, study...

Alzheimer’s risk decreases in men who take Viagra and similar prescriptions, study says


Srinagar: The erectile dysfunction drug Viagra has emerged as a potential candidate in the decades-long search for treatments for Alzheimer’s disease. Particularly intriguing was the finding that men with more frequent prescriptions had a 44 percent lower risk of Alzheimer’s.

Brain explosion; Kashmir is witnessing a much higher than average number of dementia patients and experts are exploring the possibility if it has links to the protracted conflict.

“We cannot say that the drugs are responsible, but this gives us food for thought about how to move forward,” says the British newspaper. The Guardian main author cited Said Dr. Ruth Brauer of University College London. “We now need a proper clinical trial to look at the effects of these drugs on Alzheimer’s in both women and men.”

The study, published in a world famous magazine. Neurology, The study, which included more than 260,000 men with erectile dysfunction but no cognitive impairment, tracked their use of medications, primarily PDE5 inhibitors such as sildenafil (marketed as Viagra), avanafil, vardenafil and tadalafil, over an average period of time. five years to monitor the incidence of Alzheimer’s.

While the results are intriguing, experts caution against drawing definitive conclusions, highlighting the observational nature of the study and the inability to take into account variables such as physical activity and sexual health, which could both influence drug use. as in the risk of Alzheimer’s.

However, the potential link between PDE5 inhibitors and Alzheimer’s prevention warrants further investigation, with calls for clinical trials in diverse populations to validate these findings. PDE5 inhibitors help relax blood vessels, making it easier for blood to move through the body. Animal research suggests this could improve blood flow to the brain, potentially protecting against Alzheimer’s disease. Other studies have found that these inhibitors increase levels of a substance called cGMP, which may also protect brain cells.

According to Dr. Ivan Koychev of the University of Oxford, the prospect of repurposing existing drugs for dementia prevention offers a promising approach.

However, challenges remain, including the difficulty of conducting blinded, placebo-controlled trials due to the notable effects of the drugs.

Despite differing opinions among researchers, the idea that a drug like sildenafil, typically used as needed, alters the trajectory of a chronic neurodegenerative disease like Alzheimer’s raises questions about its plausibility and mechanism of action.

The search for effective treatments for Alzheimer’s continues, and Viagra unexpectedly comes into the spotlight as a potential candidate.

“This study does not conclusively prove that erectile dysfunction drugs reduce the risk of Alzheimer’s, but it does provide good evidence that this type of drug deserves to be studied further in the future,” the BBC quoted Professor Tara Spiers as saying. -Jones, from the University of Edinburgh, and president of the British Institute. Neuroscience Association as she says.

Dr Francesco Tamagnini, a neurophysiologist at the University of Reading, said it was “a big study” but stronger evidence was needed on how the drug affected the brain.

“It could be that it exerts a therapeutic effect by directly affecting neurons (if the drug is able to cross the blood-brain barrier) and/or by increasing blood flow, but both hypotheses must be tested,” he said.

This is not the first time that pills needed to control erectile dysfunction have been linked to a positive impact on key brain cells. The results of previous studies were contradictory. While some suggested a great impact, on the contrary, others said it lacks impact. The new study, however, will prompt science to carry out comprehensive studies to take the example to the next level.




Source link

livepress.in
livepress.inhttp://livepress.in
I Am digital marketing enthusiast with a passion for helping businesses thrive in the online world. With a strong foundation in SEO, social media marketing, and content creation, I'm committed to driving impactful growth through innovative strategies.
RELATED ARTICLES

LEAVE A REPLY

Please enter your comment!
Please enter your name here

Most Popular

Recent Comments